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88,100,140,141 However, some studies have also found that CHD8 is a positive regulator of the Wnt/β-catenin signalling pathway in NPCs and negatively regulates this pathway in nonneuronal cell lines, suggesting that CHD8 may regulate Wnt signalling in a cell-specific manner

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Blüher, M., Rosenstock, J., Hoefler, J., Manuel, R