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In addition, 50 μM DPA significantly reduced BV2 cell viability after stimulation with 100 ng/mL LPS, demonstrating that n-3 DPA may inhibit microglia-NF-κB and MAPK p38 by balancing microglia M1 and M2 polarization (70)
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Thus, this highly oxidative and inflammatory peritoneal environment not only sustains the growth of ectopic lesions but also constitutes the primary cause of patient pain and infertility
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