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Despite extensive animal data suggesting efficacy across depression, anxiety, cognitive decline, and ADHD-relevant models, not a single human clinical trial exists for any mental health application

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Tirzepatide, sold as Zepbound and Mounjaro, was the last agent for 82 (64.6%), and semaglutide, sold as Wegovy and Ozempic, for 45 (35.4%), so the documented switching ran mostly from an approved Lilly medicine to a purported version of Lilly’s unapproved successor to it [1]