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A fraction of Gln in astrocytes is transported into GABAergic neurons, where it is transformed into Glu (alternatively, Gln in astrocytes is converted into Glu and then transported into GABAergic neurons), which is ultimately converted into GABA by glutamate decarboxylase [4]
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The increased ROS levels in some tumor cells are also commonly associated with decreased expression of cellular antioxidant systems
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