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Characteristics of proteins in fibrotic lung We performed the principal component analysis (PCA) of three time instances (postoperative day 0, 14 and 28 after BLM administration) (4 mice per group), which revealed significant changes in proteomes with time in BLM mice (Fig

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Recent work showed that hypoxia upregulated xCT SLC7A11 expression and increased intracellular cystine levels and GSH synthesis in multiple types of cancer cells (62, 82)