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Manuscript source: Invited manuscript Peer-review started: July 10, 2020 First decision: August 9, 2020 Article in press: September 25, 2020 Specialty type: Cell and tissue engineering Country/Territory of origin: Spain Peer-review report’s scientific quality classification Grade A (Excellent): 0 Grade B (Very good): 0 Grade C (Good): C Grade D (Fair): 0 Grade E (Poor): 0 P-Reviewer: Chen Q S-Editor: Gao CC L-Editor: Webster JR P-Editor: Li JH Contributor Information Petra Jagust, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain