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While these findings are intriguing, the leap from controlled laboratory settings to the complex biological environment of the human body is significant and uncertain

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Jia, Wei, and Jiang, publishing in the Journal of Physiology and Biochemistry in 2022, observed that NNMT is induced dynamically during beige adipogenesis in a depot-specific manner, suggesting that NNMT activity is not merely a marker of dysfunctional fat but an active participant in determining adipose tissue identity